RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-101a
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; immunofluorescence etc.
Target
TGFBR1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-101a inhibits cardiac fibrosis induced by hypoxia via targeting TGFBRI on cardiac fibroblasts
Year
2015
Function
"miR-101a exerts anti-fibrotic effects by targeting TGF-betaRi, suggesting that miR-101a plays a multi-faceted role in modulating TGF-beta signaling pathway and cardiac fibrosis."